Service by

Home Journal Issues Guide for Authors Editorial Board About Journal Aims & Scope


Original Article 


A Study to Evaluate the Safety of Second Line Antiretroviral Therapy Given To HIV Patients At Tertiary Care Hospital In Western India

Jigar P Modi*, Amita Kubavat**, Shailesh Mundhava***, Usha Lalwani****.

Abstract
Introduction: Prescription of multiple drugs are common in HIV positive individuals particularly after initiation of ART. Therefore, they are at a higher risk of drug interactions and adverse drug reactions. So monitoring of safety in drugs can be helpful to change or design future treatment protocols. Methods: In our ART plus centre patient had to come after 30 days of last visit to refill antiretroviral therapy for next month. After consultation with physician, patient was interviewed and details of any adverse drug reactions due to second line ART or with other drugs were recorded. Results: Most commonly documented ADRs were vomiting [17.02%] and itching [12.76%], followed by hyperbilirubinemia [10.64%] and GI upset [10.64%]. Nausea and vomiting were mainly recorded with tenofovir+lamivudine+atazanavir/ritonavir. There were more number of cases of hyperbilirubinemia with tenofovir+lamivudine+atazanavir/ritonavir than any other regimen. 87.24% of recorded ADRs were of mild severity, 12.76% were of moderate severity according to modified hartwieg and siegel scale. As per causality assessment 76.60 % ADRs were possible and 23.40% were probable ADRs. Conclusion: All the NACO prescribed regimens were well tolerated in majority of the patients, with mild and tolerable adverse effects. [J Modi Natl J Integr Res Med, 2018; 2018; 9(1):68-72]

Key words: Adverse Drug Reaction, HIV, Secondline ART, Safety.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Related Records
 Articles by Jigar P Modi*
Articles by Amita Kubavat**
Articles by Shailesh Mundhava***
Articles by Usha Lalwani****
on Google
on Google Scholar
Article Statistics
 Viewed: 168
Downloaded: 38
Cited: 0


How to Cite this Article
Pubmed Style

Modi JP, Kubavat A, Mundhava S, Lalwani U. A Study to Evaluate the Safety of Second Line Antiretroviral Therapy Given To HIV Patients At Tertiary Care Hospital In Western India. NJIRM. 2018; 9(1): 68-72.


Web Style

Modi JP, Kubavat A, Mundhava S, Lalwani U. A Study to Evaluate the Safety of Second Line Antiretroviral Therapy Given To HIV Patients At Tertiary Care Hospital In Western India. http://www.njirm.com/?mno=292788 [Access: June 24, 2018].


AMA (American Medical Association) Style

Modi JP, Kubavat A, Mundhava S, Lalwani U. A Study to Evaluate the Safety of Second Line Antiretroviral Therapy Given To HIV Patients At Tertiary Care Hospital In Western India. NJIRM. 2018; 9(1): 68-72.



Vancouver/ICMJE Style

Modi JP, Kubavat A, Mundhava S, Lalwani U. A Study to Evaluate the Safety of Second Line Antiretroviral Therapy Given To HIV Patients At Tertiary Care Hospital In Western India. NJIRM. (2018), [cited June 24, 2018]; 9(1): 68-72.



Harvard Style

Modi, J. P., Kubavat, A., Mundhava, S. & Lalwani, U. (2018) A Study to Evaluate the Safety of Second Line Antiretroviral Therapy Given To HIV Patients At Tertiary Care Hospital In Western India. NJIRM, 9 (1), 68-72.



Turabian Style

Modi, Jigar P, Amita Kubavat, Shailesh Mundhava, and Usha Lalwani. 2018. A Study to Evaluate the Safety of Second Line Antiretroviral Therapy Given To HIV Patients At Tertiary Care Hospital In Western India. National Journal of Integrated Research in Medicine, 9 (1), 68-72.



Chicago Style

Modi, Jigar P, Amita Kubavat, Shailesh Mundhava, and Usha Lalwani. "A Study to Evaluate the Safety of Second Line Antiretroviral Therapy Given To HIV Patients At Tertiary Care Hospital In Western India." National Journal of Integrated Research in Medicine 9 (2018), 68-72.



MLA (The Modern Language Association) Style

Modi, Jigar P, Amita Kubavat, Shailesh Mundhava, and Usha Lalwani. "A Study to Evaluate the Safety of Second Line Antiretroviral Therapy Given To HIV Patients At Tertiary Care Hospital In Western India." National Journal of Integrated Research in Medicine 9.1 (2018), 68-72. Print.



APA (American Psychological Association) Style

Modi, J. P., Kubavat, A., Mundhava, S. & Lalwani, U. (2018) A Study to Evaluate the Safety of Second Line Antiretroviral Therapy Given To HIV Patients At Tertiary Care Hospital In Western India. National Journal of Integrated Research in Medicine, 9 (1), 68-72.



AUTHOR LOGIN

REVIEWER LOGIN

Indexed In

 National Journal of Integrated Research in Medicine

Publication by Association of Health Professionals and Health Educators

Open access peer reviewed Journal -  Publication Ethics Policies for Medical Journals  - Retracted Article 

    eISSN : 0975-9840, pISSN:  2230 - 9969 

Now Indexed in National Library of Medicine Catalog,

Indexed in PubMed (for Selected Citation)

Indexed in Index Medicus for the South-East Asian Region

Indexed in Index Copernicus (IC Value 66.37)

Search Your article in Index Copernicus

ISRA Journal Impact Factor: 5.39,  Scientific Journal Impact Factor = 2.507

WHO-HINARI, Index Scholar,

Science Central.com (Score 23.0)

 

  http://www.impactfactorservice.com/assets/images/logo.png     

Included in Open J-Gate, getCITED, connotea, Open Directory Project,

 EQUATOR Network,Ulrich’s Database of ProQuest, MedWorm Publisher,Connect Journals & EBSCO Publishing, ISC Database, New Jour, PSOAR Database, JournalSeek, ourGlocal Journal Database,Cochrane Menstrual Disorders and Subfertility Group, Islamic world science citation center,   

open access journals search engine, Impact Index, Journal Index,Citefactor.org, Directory of Research Journals Indexing (DRJI), Sjournals Index, Open Academic Journals Index, SIS database

 

 --------------------------------------------------------------------------------

List of Journals Indexed for MEDLINE

The List of Journals Indexed for MEDLINE publication ceased with the 2008 edition. The NLM Catalog can be used to obtain a list of currently indexed MEDLINE titles; select the Limit for Current Subsets called "Currently indexed in MEDLINE."

The List of Serials Indexed for Online Users online publication is designed to provide bibliographic information for serials from which articles are indexed with the MeSH® vocabulary and cited in MEDLINE®, the backbone of the NLM PubMed® database. More detailed bibliographic data and information about indexing coverage for serials cited in MEDLINE/PubMed can be found in LocatorPlus®, the NLM online catalog, and the NLM Catalog, an Entrez database.

Journals Recently Accepted by NLM for Inclusion in MEDLINE lists titles selected by LSTRC which meets three times per year in February, June, and October. Results from those meetings appear online about six weeks after each meeting, both on the Web page and in the NLM Catalog.

Previous print versions of the List of Journals Indexed for MEDLINE might be available from the U.S. Government Printing Office (GPO). Information about ordering documents from GPO is available at http://www.nlm.nih.gov/pubs/pubcat.html#ordering.

 
 



The articles in National Journal of Integrated Research in Medicine are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.