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Rapid Diagnostic Test for the Discrimination between Types of Meningitis

Nishant Pujara*, Vachan Mehta**, Kinnari Thacker***, Jay Shah****.

Abstract
Background & Aim: there is a need for an easy and comprehensive test to diagnose Acute Bacterial Meningitis timely. Routine use of CSF CRP in diagnosing acute bacterial meningitis could be a rapid, reliable and easy method for diagnosis of meningitis. Hence the aim of this study is to evaluate whether C-reactive protein and adenosine deaminase levels could be used to differentiate the various types of meningitis in adults. Methods: Patients were divided into three groups. Group I comprised of 10 cases of pyogenic meningitis based on clinical features usually acute in onset. They were associated with otitis media, sinusitis and signs of meningeal irritation. Group II comprised of 62 cases of tuberculosis meningitis, which included insidious in onset, maybe associated with TB of other organs or signs of meningeal irritation. Group III comprised of 18 cases of viral meningitis based on clinical presentation, usually acute in onset with signs of meningeal irritation. Results: CRP level in pyogenic meningitis cases were found to be significantly higher as compared to the other two groups. It was found that none of the cases of pyogenic and viral meningitis had positive ADA values. Conclusion: On the basis of above based result and discussion it was concluded that ADA activity in CSF is elevated in tuberculous meningitis. CSF-CRP levels can reliably discriminate between pyogenic and non-pyogenic meningitis. [N Pujara Natl J Integr Res Med, 2018; 9(1):12-15]

Key words: ADA, CSF, Evaluation, Meningitis


 
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How to Cite this Article
Pubmed Style

Pujara N, Mehta V, Thacker K, Shah J. Rapid Diagnostic Test for the Discrimination between Types of Meningitis. NJIRM. 2018; 9(1): 12-15.


Web Style

Pujara N, Mehta V, Thacker K, Shah J. Rapid Diagnostic Test for the Discrimination between Types of Meningitis. http://www.njirm.com/?mno=292770 [Access: April 26, 2018].


AMA (American Medical Association) Style

Pujara N, Mehta V, Thacker K, Shah J. Rapid Diagnostic Test for the Discrimination between Types of Meningitis. NJIRM. 2018; 9(1): 12-15.



Vancouver/ICMJE Style

Pujara N, Mehta V, Thacker K, Shah J. Rapid Diagnostic Test for the Discrimination between Types of Meningitis. NJIRM. (2018), [cited April 26, 2018]; 9(1): 12-15.



Harvard Style

Pujara, N., Mehta, V., Thacker, K. & Shah, J. (2018) Rapid Diagnostic Test for the Discrimination between Types of Meningitis. NJIRM, 9 (1), 12-15.



Turabian Style

Pujara, Nishant, Vachan Mehta, Kinnari Thacker, and Jay Shah. 2018. Rapid Diagnostic Test for the Discrimination between Types of Meningitis. National Journal of Integrated Research in Medicine, 9 (1), 12-15.



Chicago Style

Pujara, Nishant, Vachan Mehta, Kinnari Thacker, and Jay Shah. "Rapid Diagnostic Test for the Discrimination between Types of Meningitis." National Journal of Integrated Research in Medicine 9 (2018), 12-15.



MLA (The Modern Language Association) Style

Pujara, Nishant, Vachan Mehta, Kinnari Thacker, and Jay Shah. "Rapid Diagnostic Test for the Discrimination between Types of Meningitis." National Journal of Integrated Research in Medicine 9.1 (2018), 12-15. Print.



APA (American Psychological Association) Style

Pujara, N., Mehta, V., Thacker, K. & Shah, J. (2018) Rapid Diagnostic Test for the Discrimination between Types of Meningitis. National Journal of Integrated Research in Medicine, 9 (1), 12-15.



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