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Diastolic Dysfunction In Asymptomatic Type 2 Diabetes Mellitus Evaluated By Echocardiography

Satyam Patel MD*, Hetal Chauhan MD**, Gunjan Amin MD***.

Abstract
Introduction: As per the latest edition of International Diabetes Federation (IDF) Diabetes Atlas, diabetes mellitus now affects almost 371 million people worldwide, and majorities (90%-95%) have type 2 DM, which is measured metabolic cum vascular disease. There is marked increase in incidence of congestive heart failure, coronary artery disease in diabetic patients. Despite similar left ventricular systolic dysfunction, patients with diabetes have more pronounced heart failure symptoms and adverse prognosis compared with non-diabetic; one putative explanation for these discrepancies is LVDD in DM. The diastolic abnormalities are present in diabetic patients without overt diabetic complications of cardiovascular system, reinforcing the importance of early examination of ventricular function. Methods: This was a simple randomized study, conducted from August 2012 to October 2014. 50 patients with type 2 DM who had no symptoms of cardiovascular disease with normal BP and normal ECG were enrolled. Informed consent was obtained from the patients and they underwent a thorough physical examination, supported by laboratory investigations. A Doppler 2D echo was done in each patient and a calculation of LV ejection fraction, LA dimension; E velocity, A velocity and E/A ratio, IVRT and DT of E were done. Results: Our study consisted of 50 patients with type 2 DM, 27(54%) were males and 23 (46%) females. Majority of patients were in the age group of 5070 years. Diastolic dysfunction was present in 26 (52%) patients out of whom 16 were males and 12 females. There was a linear increase in prevalence of diastolic dysfunction with increasing age, increased duration of diabetes mellitus and increasing HbA1c levels. Moreover statistically significant are Ejection Fraction, E/A Ratio, IVRT (msec), DT of E such as echocardiographic measurement with different studies. Conclusion: LV diastolic dysfunction is an early manifestation of diabetic cardiomyopathy. Its prevalence correlates with duration of diabetes, HbA1c values. LVDD contributes significantly to morbidity of CHF in diabetic patients. LVDD may be the 1st stage of Diabetic cardiomyopathy and should be screened for LVDD.[Satyam P NJIRM 2017; 8(6):66-70]

Key words: Type 2 diabetes mellitus, LV diastolic dysfunction, Echocardiography.


 
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How to Cite this Article
Pubmed Style

MD SP, MD HC, MD GA. Diastolic Dysfunction In Asymptomatic Type 2 Diabetes Mellitus Evaluated By Echocardiography. NJIRM. 2017; 8(6): 66-70.


Web Style

MD SP, MD HC, MD GA. Diastolic Dysfunction In Asymptomatic Type 2 Diabetes Mellitus Evaluated By Echocardiography. http://www.nicpdjournals.com/?mno=288238 [Access: January 19, 2018].


AMA (American Medical Association) Style

MD SP, MD HC, MD GA. Diastolic Dysfunction In Asymptomatic Type 2 Diabetes Mellitus Evaluated By Echocardiography. NJIRM. 2017; 8(6): 66-70.



Vancouver/ICMJE Style

MD SP, MD HC, MD GA. Diastolic Dysfunction In Asymptomatic Type 2 Diabetes Mellitus Evaluated By Echocardiography. NJIRM. (2017), [cited January 19, 2018]; 8(6): 66-70.



Harvard Style

MD, S. P., MD, H. C. & MD, G. A. (2017) Diastolic Dysfunction In Asymptomatic Type 2 Diabetes Mellitus Evaluated By Echocardiography. NJIRM, 8 (6), 66-70.



Turabian Style

MD, Satyam Patel, Hetal Chauhan MD, and Gunjan Amin MD. 2017. Diastolic Dysfunction In Asymptomatic Type 2 Diabetes Mellitus Evaluated By Echocardiography. National Journal of Integrated Research in Medicine, 8 (6), 66-70.



Chicago Style

MD, Satyam Patel, Hetal Chauhan MD, and Gunjan Amin MD. "Diastolic Dysfunction In Asymptomatic Type 2 Diabetes Mellitus Evaluated By Echocardiography." National Journal of Integrated Research in Medicine 8 (2017), 66-70.



MLA (The Modern Language Association) Style

MD, Satyam Patel, Hetal Chauhan MD, and Gunjan Amin MD. "Diastolic Dysfunction In Asymptomatic Type 2 Diabetes Mellitus Evaluated By Echocardiography." National Journal of Integrated Research in Medicine 8.6 (2017), 66-70. Print.



APA (American Psychological Association) Style

MD, S. P., MD, H. C. & MD, G. A. (2017) Diastolic Dysfunction In Asymptomatic Type 2 Diabetes Mellitus Evaluated By Echocardiography. National Journal of Integrated Research in Medicine, 8 (6), 66-70.



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